JMJD2C (KDM4C) Homogeneous Assay Kit

Product Code
AMS.50415-1
$0.00
Order Support
Shipping Information
Product Updates
  • Keep up to date with product offers, resources and news

  • Sign up

The JMJD2C Homogeneous Assay Kit is designed to measure JMJD2C activity for screening and profiling applications. JMJD2C is a JumonjiC (JmjC) domain containing histone lysine demethylase that exhibits demethylation activity toward H3-K9Me3 and H3-K36Me3. The JMJD2C Homogeneous Assay Kit comes in a convenient AlphaLISA® format (Scheme 1)|with biotinylated histone H3 peptide substrate|primary antibody|demethylase assay buffer|and purified JMJD2C for 96 enzyme reactions. The key to the JMJD2C Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit|only three simple steps on a microtiter plate are required for methyltransferase detection. First|a sample containing JMJD2C enzyme is incubated with the biotinylated substrate. Next|acceptor beads and primary antibody are added|then donor beads|followed by reading the Alpha-counts.
More Information
SKU AMS.50415-1
Size 96 reactions
Application Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Gene synonyms KDM4C, GASC1, AlphaLISA, Alphascreen, Alpha Lisa, Alpha screen
Storage 12 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Shipping Temp -80C (dry ice)
Supplier Name BPS