JMJD2C (KDM4C) Homogeneous Assay Kit
Product Code
AMS.50415-1
$0.00
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The JMJD2C Homogeneous Assay Kit is designed to measure JMJD2C activity for screening and profiling applications. JMJD2C is a JumonjiC (JmjC) domain containing histone lysine demethylase that exhibits demethylation activity toward H3-K9Me3 and H3-K36Me3. The JMJD2C Homogeneous Assay Kit comes in a convenient AlphaLISA® format (Scheme 1)|with biotinylated histone H3 peptide substrate|primary antibody|demethylase assay buffer|and purified JMJD2C for 96 enzyme reactions. The key to the JMJD2C Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit|only three simple steps on a microtiter plate are required for methyltransferase detection. First|a sample containing JMJD2C enzyme is incubated with the biotinylated substrate. Next|acceptor beads and primary antibody are added|then donor beads|followed by reading the Alpha-counts.
SKU | AMS.50415-1 |
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Size | 96 reactions |
Application | Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
Gene synonyms | KDM4C, GASC1, AlphaLISA, Alphascreen, Alpha Lisa, Alpha screen |
Storage | 12 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |