Hyaluronic Acid Ladders Standards
Purified single-size hyaluronic acid oligomers
Select-HA™: Hyaluronic acid (HA) Oligo-HAs are purified single-size hyaluronic acid oligomers prepared by testicular hyaluronidase digestion. Data sheets are provided for the absolute average molecular weight determination of each Select-HA™ as characterized by SEC-MALLS (size exclusion chromatography multiple angle laser light scattering). All other currently available commercial Hyaluronic Acid preparations have much greater size heterogeneity and run as a smear, but any given Select-HA™ runs as a distinct band.
Select-HA™ Ladder
We have assembled different mixtures of linear Select-HA™ polymers of very defined size ranges for use as size standards on gels or other separation methods. The sizes (masses) of the Select-HA™ samples have been determined by SEC-MALLS.
Two ranges for higher (HiLadder) or lower molecular weight (LoLadder) HA are now available.
Tagged Select-HA™: A fluorescent or biotinylated narrow-size distribution HA polymer with a single fluorescein or biotin group.
Mega-HA™ Ladder
We have compiled a mixture of streptavidin/biotin Select-HA™ complexes of very defined size ranges for use as size standards on gels or other separation methods. The size (mass) of the starting Select-HA™ sample has been determined by SEC-MALLS and the resulting complexes migrate on gels with linear correlation to the expected polymeris mass. The ladder contains the original size material plus larger complexes that are 2 times, or 3 times, or 4 times the size of the starting Select-HA™ polymer.
Nano-HA™
A variety of different sizes of HA oligosaccharides are available from HA 4-24 (note: the product number signifies the number of monosaccharides thus HA12 is twelve monosaccharides long).