Human IL-4 Protein, premium grade
Product Code
AMS.IL4-H4218-20ug
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Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
| SKU | AMS.IL4-H4218-20ug |
|---|---|
| Size | 20 ug |
| Species | Human |
| Expression Host | HEK293 |
| Gene symbol | IL-4 |
| aa sequence | His 25 - Ser 153 |
| Tag | Untagged |
| Label/Conjugate | Unconjugated |
| Accession No | AAH67514 |
| Gene id | ActiveMax® Human IL-4, Tag Free (IL4-H4218) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P05112-1). |
| Gene description | Human |
| Gene synonyms | IL4,BCGF1,BSF1 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | RT |
| Supplier Name | ACROBiosystems Inc. |
| Research Areas | Immunology |
