FcGRIIIA (CD16a) Lentivirus

Name: FcGRIIIA (CD16a) Lentivirus
Brand: AMS.79876
SKU: AMS.79876
Availability: InStock

Product Code

AMS.79876

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Overview

Fc Gamma Receptor IIIa (FcGRIIIA; Fc?RIIIA)/ also known as CD16a/ is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis/ antibody-dependent cytotoxicity and clearance of immune complexes. The human Fc?RIIIa displays a dimorphism in the position of residue 158. One allele (V158) encodes a higher Fc affinity receptor variant with a valine at amino acid residue 158/ and the other (F158) encodes a lower Fc affinity receptor variant having a phenylalanine at amino acid residue 158.
The FcGRIIIA Lentivirus are replication incompetent/ HIV-based/ VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells/ including primary and non-dividing cells. The particles contain a FcGRIIIA gene (NM_001127593.1; high affinity V158 variant) driven by a CMV promoter.

Product Specifications

More Information
SKU	AMS.79876
Size	500 ul x 2
Species	Human
Application	1. Transient expression of FcGRIIIA in target cells. 2. Generation of stable cell line expressing FcGRIIIA with Geneticin (G418) selection.
Gene synonyms	CD16a Lentivirus
Storage	Lentiviruses are shipped with dry ice. For long term storage/ it is recommended to store the virus at -80C. Avoid repeated freeze-thaw cycles. Titers can drop significantly with each freeze-thaw cycle.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS

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FcGRIIIA (CD16a) Lentivirus

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