FcGR2B CHO K1 Recombinant Cell Line

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AMS.79511
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Recombinant FcGR2B-CHO K1 cell line stably expressing full length human FcGR2B (isoform 1/ GenBank Accession Number NM_004001.4). Crosslinking of antibodies bound to target by FcGR-expression cells can promote receptor clustering and increase downstream signaling. FcGR2B crosslinking is important for anti-TNFR receptor antibodies.
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SKU AMS.79511
Size 2 vials
Species Human
Cell Line CHO
Tissue Type Ovary
Application • Screen for activators or inhibitors of antibody-mediated signaling by coculturing with the FcGR2B CHO K1 cells. • Characterize the agonist activity of antibodies by crosslinking to the FcGR2B receptor.
Gene synonyms Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb
Storage Store in liquid nitrogen immediately upon receipt.
Shipping Temp -80C (dry ice)
Supplier Name BPS
Research Areas Immunology
For more details visit our Immunotherapy page >