EZH2 (Y641N) /EED/SUZ12/RbAp48/AEBP2, His-tag, FLAG-tag

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AMS.51028
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Mutant version of our regular EZH2 5-member complex (Cat. #51004), but with a Tyr-to-Asn mutation on a.a. 646 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), a.a. 2-end, Y646N*, with N-terminal His-tag, MW= 86 kDa, human EED (NM_003797), a.a. 2-end with N-terminal FLAG-tag, MW= 51 kDa, human SUZ12 (NM_015355), a.a. 2-end with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (NM_153207), a.a. 2- end with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (NM_005610), a.a. 2-end with N-terminal His-tag, MW = 48 kDa, co-expressed in a baculovirus expression system.
More Information
SKU AMS.51028
Size 20 ug
Species Human
Expression Host Insect Cells, Sf9 Cells
aa sequence 2-end (all components)
Tag His, FLAG
Tag position N-terminal
Application Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex.
Accession No NM_004456 (EZH2), NM_003797(EED), NM_015355 (SUZ12), NM_153207(AEBP2), NM_005610(RbAP48)
Gene id NM_004456 (EZH2), NM_003797(EED), NM_015355 (SUZ12), NM_153207(AEBP2), NM_005610(RbAP48)
Gene synonyms KTM6A, EZH2, PRC2, Enhancer Of Zeste Homolog 2, EZH2 (Y646N), EZH, Retinoblastoma Binding Protein 4 (RBBP4)
Format Aqueous buffer solution
Storage >= 6 months at -80C
Shipping Temp -80C
Supplier Name BPS
Research Areas Epigenetics
For more details visit our Histone Methylation page >