EZH2 (P132S)/EED/SUZ12/RbAp48/AEBP2, FLAG-tag, His-tag

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AMS.51019
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Mutant version of BPS's regular EZH2 5-member complex (Cat. # 51004), but with a Pro-to-Ser mutation on a.a. 132 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), (a.a. 2-end; P132S) with N-terminal His-tag, MW= 86 kDa, human EED (NM_003797) (a.a. 2-end) with N-terminal FLAG-tag, MW= 51 kDa, human SUZ12 (NM_015355) (a.a. 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (NM_153207) (a.a. 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (NM_005610) (a.a. 2-end) with N-terminal His-tag, MW = 48 kDa, co-expressed in a baculovirus expression system.
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SKU AMS.51019
Size 20 ug
Species Human
Expression Host Insect Cells, Sf9 Cells
aa sequence 2-end (all components)
Tag His, FLAG
Tag position N-terminal
Application Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex.
Accession No NM_004456 (EZH2), NM_003797(EED), NM_015355 (SUZ12), NM_153207(AEBP2), NM_005610(RbAP48)
Gene id NM_004456 (EZH2), NM_003797(EED), NM_015355 (SUZ12), NM_153207(AEBP2), NM_005610(RbAP48)
Gene synonyms KTM6A, EZH2, PRC2, Enhancer Of Zeste Homolog 2, RBAP48, Retinoblastoma Binding Protein 4 (RBBP4), hEED, Suppressor Of Zeste 12 Homolog, CHET9, JJAZ1; AE binding protein 2, Adipocyte Enhancer binding protein 2, EZH
Format Aqueous buffer solution
Storage >6 months at -70C.
Shipping Temp -80C
Supplier Name BPS
Research Areas Epigenetics
For more details visit our Histone Methylation page >