Cynomolgus IL-31 Protein, His Tag
Product Code
AMS.IL1-C5245-1mg
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IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor C (OSMRC) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
SKU | AMS.IL1-C5245-1mg |
---|---|
Size | 1 mg |
Species | Monkey, Cynomolgus |
Expression Host | HEK293 |
Gene symbol | IL-31 |
Tag | His |
Accession No | N/A |
Gene synonyms | IL-31,IL31,Interleukin-31 |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |