CSL Reporter - HEK293 Cell line
Product Code
AMS.79754
$0.00
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The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) stably integrated into HEK293 cells. Transfection of this cell line with a Notch expression vector and activation of the Notch pathway leads to expression of luciferase reporter. This cell line is validated with a Notch1DelE expression vector/ which is constitutively processed by ?-secretase/ leading to the release of NICD and the expression of luciferase.
SKU | AMS.79754 |
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Size | 2 vials |
Species | Human |
Cell Line | HEK293 |
Application | • Monitor Notch signaling pathway activity. • Screen for inhibitors of the Notch signaling pathway • Test synthetic Notch receptors (synNotch) or other genetic constructs that conditionally activate the CSL promoter |
Gene synonyms | Notch reporter, PKA reporter, cAMP reporter, luciferase reporter , CSL reporter, CBF1 reporter, RBP-J reporter, Cell based assay kit, cell-based assay, reporter assay kit |
Storage | Immediately upon receipt/ store cells in liquid nitrogen. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |