CBL-B TR-FRET Assay Kit
Product Code
AMS.79575
$0.00
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Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B) is an E3 ubiquitinprotein ligase that functions as a negative regulator of T-cell activation. It is a promising drug target in cancer immunotherapy. The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled Ubiquitin and a terbium-labeled anti-CBL-B antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps|making it especially suitable for high throughput screening applications.
SKU | AMS.79575 |
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Size | 384 reactions |
Application | Great for screening small molecular inhibitors for drug discovery and HTS applications. |
Gene synonyms | UBE1, UBA1, ubcH5b, UBE2D2, E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, CBL, CBLB, HTRF, cblb |
Storage | Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |