ARE Reporter Kit (Nrf2 Antioxidant Pathway )
Product Code
AMS.60514
$0.00
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The ARE Reporter kit is designed for monitoring the activity of the Nrf2 antioxidant pathway in cultured cells. The kit contains a transfection-ready ARE luciferase reporter vector|which is an Nrf2 pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized ARE responsive elements located upstream of a minimal promoter. The ARE reporter is premixed with a constitutively expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively expressing Renilla luciferase vector as negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter|without any additional response elements. This negative control is critical to determining pathway-specific effects and background luciferase activity.
SKU | AMS.60514 |
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Size | 500 reactions |
Application | • Monitor Nrf2 antioxidant response pathway activity. • Screen for activators or inhibitors of the Nrf2 antioxidant response pathway. • Study effects of RNAi or gene overexpression on the activity of the Nrf2 pathway. |
Gene synonyms | ARE reporter, Nrf2 reporter, Nrf |
Format | assay kit |
Storage | Stable at least 12 months from date of receipt# when stored as directed (-20C) |
Shipping Temp | -20C |
Supplier Name | BPS |
Research Areas | Immunology |