AP1 Reporter Kit (JNK Pathway)

Product Code
AMS.60612
$0.00
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The AP1 Reporter Kit is designed for monitoring the activity of the JNK signaling pathway and the transcriptional activity of AP1 in cultured cells. The kit contains a transfection-ready AP1 luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized AP1 responsive elements located upstream of a minimal promoter. The AP1 reporter is premixed with a constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter|without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.
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SKU AMS.60612
Size 500 reactions
Application • Monitor cAMP/PKA signaling pathway activity.
• Screen for activators or inhibitors of PKA or cAMP/PKA pathway components.
• Study effects of RNAi or gene overexpression on the activity of the cAMP/PKA pathway.
Gene synonyms JNK reporter, SAPK reporter
Format assay kit
Storage Stable at least 12 months from date of receipt# when stored as directed (-20C)
Shipping Temp -20C
Supplier Name BPS
Research Areas Immunology
For more details visit our Immunotherapy page >