Anti-STAT3 Rabbit Monoclonal Antibody

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Monoclonal antibody for STAT3 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IF, IHC, ICC, WB. Reactive species: Human STAT3 information: Molecular Weight: 88068 MW; Subcellular Localization: Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1; Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
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SKU M00007-2
Size 100 ul
Host species Rabbit
Gene symbol STAT3
Application WB, IF, IP
Species reactivity Human
Accession No P40763
Gene id 6774
Gene synonyms Signal transducer and activator of transcription 3;Acute-phase response factor;STAT3;APRF;
Format Liquid
Storage At -20°C for one year. Avoid repeated freezing and thawing.
Shipping Temp Dry Ice
Supplier Name Boster Biological Technology Ltd
Research Areas Cardiovascular, Cancer Research, Stem Cells, Epigenetics