Anti-Raf1 Rabbit Monoclonal Antibody

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Monoclonal antibody for Raf-1/RAF1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat Raf-1/RAF1 information: Molecular Weight: 73052 MW; Subcellular Localization: Cytoplasm. Cell membrane. Mitochondrion. Nucleus. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes. Phosphorylation at Ser-259 impairs its membrane accumulation. Recruited to the cell membrane by the active Ras protein. Phosphorylation at Ser-338 and Ser-339 by PAK1 is required for its mitochondrial localization. Retinoic acid- induced Ser-621 phosphorylated form of RAF1 is predominantly localized at the nucleus; Tissue Specificity: In skeletal muscle, isoform 1 is more abundant than isoform 2.
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SKU M00446-1
Size 100 ul
Host species Rabbit
Gene symbol RAF1
Application WB, IF
Species reactivity Human, Mouse, Rat
Accession No P04049
Gene id 5894
Gene synonyms RAF proto-oncogene serine/threonine-protein kinase;;Proto-oncogene c-RAF;cRaf;Raf-1;RAF1;RAF;
Format Liquid
Storage At -20°C for one year. Avoid repeated freezing and thawing.
Shipping Temp Dry Ice
Supplier Name Boster Biological Technology Ltd
Research Areas Cancer Research, Metabolism