Anti-Raf1 Rabbit Monoclonal Antibody
Product Code
M00446-1
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Monoclonal antibody for Raf-1/RAF1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat Raf-1/RAF1 information: Molecular Weight: 73052 MW; Subcellular Localization: Cytoplasm. Cell membrane. Mitochondrion. Nucleus. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes. Phosphorylation at Ser-259 impairs its membrane accumulation. Recruited to the cell membrane by the active Ras protein. Phosphorylation at Ser-338 and Ser-339 by PAK1 is required for its mitochondrial localization. Retinoic acid- induced Ser-621 phosphorylated form of RAF1 is predominantly localized at the nucleus; Tissue Specificity: In skeletal muscle, isoform 1 is more abundant than isoform 2.
SKU | M00446-1 |
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Size | 100 ul |
Host species | Rabbit |
Gene symbol | RAF1 |
Application | WB, IF |
Species reactivity | Human, Mouse, Rat |
Accession No | P04049 |
Gene id | 5894 |
Gene synonyms | RAF proto-oncogene serine/threonine-protein kinase;2.7.11.1;Proto-oncogene c-RAF;cRaf;Raf-1;RAF1;RAF; |
Format | Liquid |
Storage | At -20°C for one year. Avoid repeated freezing and thawing. |
Shipping Temp | Dry Ice |
Supplier Name | Boster Biological Technology Ltd |
Research Areas | Cancer Research, Metabolism |