Anti-Parkin PARK2 Rabbit Monoclonal Antibody

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Monoclonal antibody for PARK2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat PARK2 information: Molecular Weight: 51641 MW; Subcellular Localization: Cytoplasm, cytosol . Nucleus. Endoplasmic reticulum. Mitochondrion . Mainly localizes in the cytosol. Co-localizes with SYT11 in neutrites. Co-localizes with SNCAIP in brainstem Lewy bodies. Mitochondrial localization gradually increases with cellular growth. Also relocates to dysfunctional mitochondria that have lost the mitochondrial membrane potential; recruitment to mitochondria is PINK1- dependent; Tissue Specificity: Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons from kainate-mediated apoptosis. Found in serum (at protein level).
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SKU M00127
Size 100 ul
Host species Rabbit
Gene symbol PARK2
Application WB, IF, IP
Species reactivity Human, Mouse, Rat
Accession No O60260
Gene id 5071
Gene synonyms E3 ubiquitin-protein ligase parkin;Parkin;6.3.2.-;Parkinson juvenile disease protein 2;Parkinson disease protein 2;PARK2;PRKN;
Format Liquid
Storage At -20°C for one year. Avoid repeated freezing and thawing.
Shipping Temp Dry Ice
Supplier Name Boster Biological Technology Ltd
Research Areas Metabolism, Neuroscience