Anti-p62/SQSTM1 Rabbit Monoclonal Antibody

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Monoclonal antibody for p62/SQSTM1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IF, ICC, WB. Reactive species: Human, Mouse, Rat p62/SQSTM1 information: Molecular Weight: 47687 MW; Subcellular Localization: Cytoplasm. Late endosome. Lysosome. Cytoplasmic vesicle, autophagosome. Nucleus. Endoplasmic reticulum. Cytoplasm, P-body. Sarcomere (By similarity). In cardiac muscles localizes to the sarcomeric band (By similarity). Commonly found in inclusion bodies containing polyubiquitinated protein aggregates. In neurodegenerative diseases, detected in Lewy bodies in Parkinson disease, neurofibrillary tangles in Alzheimer disease, and HTT aggregates in Huntington disease. In protein aggregate diseases of the liver, found in large amounts in Mallory bodies of alcoholic and nonalcoholic steatohepatitis, hyaline bodies in hepatocellular carcinoma, and in SERPINA1 aggregates. Enriched in Rosenthal fibers of pilocytic astrocytoma. In the cytoplasm, observed in both membrane-free ubiquitin- containing protein aggregates (sequestosomes) and membrane- surrounded autophagosomes. Colocalizes with TRIM13 in the perinuclear endop
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SKU M00300
Size 100 ul
Host species Rabbit
Gene symbol SQSTM1
Application WB, IF
Species reactivity Human, Mouse, Rat
Accession No Q13501
Gene id 8878
Gene synonyms Sequestosome-1;EBI3-associated protein of 60 kDa;EBIAP;p60;Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;Ubiquitin-binding protein p62;SQSTM1;ORCA, OSIL;
Format Liquid
Storage At -20°C for one year. Avoid repeated freezing and thawing.
Shipping Temp Dry Ice
Supplier Name Boster Biological Technology Ltd
Research Areas Cardiovascular, Cancer Research, Epigenetics, Metabolism