Anti-CD19 CAR negative control/ NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28 transmembrane motif)

Product Code
79854
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Anti-CD19 CAR negative control/NFAT-luciferase reporter Jurkat cell line is a double stable cell line expressing anti-CD19 CAR negative control and NFAT-luciferase reporter. The anti-CD19 CAR negative control consists of anti-CD19 scFv linked to the CD28 transmembrane motif without any intracellular signaling domains. The reporter cell line has been validated for anti- CD19 expression by FACS/ while the stimulation by target cells including CD19/CHO recombinant cell line has not activated the luciferase reporter gene in this cell line. The cell line can be used for the negative control of anti-CD19 CAR/Jurkat-NFAT cell line (/ #79853). 
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SKU 79854
Size 2 vials
Alternate SKU AMS.79854
Application • Validate different CAR designs and constructs for their specificity/ efficacy and potency before proceeding into patient-derived primary T cells.
• Intracellular co-stimulatory and activation domain comparison.

Storage Immediately upon receipt/ store in liquid nitrogen.
Shipping Temp -80C (dry ice)
Supplier Name BPS