Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule

Name: Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule
Brand: AMS.100761-1
SKU: AMS.100761-1
Availability: InStock

Product Code

AMS.100761-1

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Overview

The Anti-BCMA-Anti-CD19-Anti-CD3-His Trispecific Antibody is engineered to bind to three different targets simultaneously: 1) BCMA, a B cell antigen that is highly expressed by mature B cells and malignant myeloma cells, 2) CD19, a B-cell marker that is a target for many leukemias and lymphomas, and 3) CD3, a T cell receptor activation signal that leads to cytokine secretion. The multi-functionality of this trispecific antibody allows it to bind to BCMA and CD19 on the tumor cell and CD3 on T cells simultaneously, thus bringing T lymphocytes closer to the cancer cells. The binding event targets the tumor while providing co-stimulatory signals that promote T cell expansion and cytotoxicity against BCMA+ and CD19+ cancer cells.

Product Specifications

More Information
SKU	AMS.100761-1
Size	50 µg
Species	Human
isotype	BiTE, variable regions only
Application	This product is for research use only. It is not suitable for human diagnostic or therapeutic use. The anti-BCMA-anti CD19-anti-CD3 can be used for studying BCMA+ cancer cell-mediated T cell activation, using either primary T cells or reporter cell lin
Gene synonyms	Cluster of Differentiation 19 antibody, B-Lymphocyte Surface Antigen B4 antibody, CVID3 antibody, B-cell maturation antigen antibody, TNFRSF17 antibody, CART antibody, 100761-1, 100761-2
Storage	Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles.
Shipping Temp	-80°C (dry ice)
Supplier Name	BPS Bioscience Inc

For more details visit our Immunotherapy: Bispecific and trispecific antibodies page >For more details visit our CAR-T Cell Research page >

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Affordable & consistent controls from 50 tumor cell lines, ideal for IHC, in situ hybridization & NGS applications.

Affordable & consistent controls from 50 tumor cell lines, ideal for IHC, in situ hybridization & NGS applications.

Affordable & consistent controls from 50 tumor cell lines, ideal for IHC, in situ hybridization & NGS applications.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

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The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

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The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

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AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

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AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

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AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

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We provide the most advanced method for gene and shRNA delivery with an extensive collection of viral particles as well as a range of custom services.

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We provide the most advanced method for gene and shRNA delivery with an extensive collection of viral particles as well as a range of custom services.

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ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

Prepared from Arthrobacter luteus, Zymolyase has a highly effective lytic activity against yeast cell walls.

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Prepared from Arthrobacter luteus, Zymolyase has a highly effective lytic activity against yeast cell walls.

Prepared from Arthrobacter luteus, Zymolyase has a highly effective lytic activity against yeast cell walls.

Prepared from Arthrobacter luteus, Zymolyase has a highly effective lytic activity against yeast cell walls.

Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule

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