ActiveMax® Human TNF-alpha Protein, Tag Free, low endotoxin (active trimer) (MALS verified)

Name: ActiveMax® Human TNF-alpha Protein, Tag Free, low endotoxin (active trimer) (MALS verified)
Brand: AMS.TNA-H4211-25ug
SKU: AMS.TNA-H4211-25ug
Price: 105 USD
Availability: InStock

Product Code

AMS.TNA-H4211-25ug

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$105.00

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Overview

Tumor necrosis factor alpha (TNF?) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNF? is in the regulation of immune cells. TNF? is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF? production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNF? is used as an immunostimulant under the INN tasonermin. TNF? can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

Product Specifications

More Information
SKU	AMS.TNA-H4211-25ug
Size	25 ug
Species	Human
Expression Host	HEK293
Gene symbol	TNF-alpha
aa sequence	Val 77 - Leu 233
Tag	Untagged
Label/Conjugate	Unconjugated
Accession No	NP_000585.2
Gene synonyms	DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNF?
Format	Powder
Storage	-20?
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.
Research Areas	Immunology

For more details visit our ActiveMax® Human Cytokines page >

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Immobilized ActiveMax® Human TNF-alpha, Tag Free, low endotoxin (active trimer) (MALS verified) (Cat. No. TNA-H4211) at 2 ?g/mL (100 ?L/well) can bind Humira with a linear range of 0.2-2 ng/mL (QC tested).

ActiveMax® Human TNF-alpha, Tag Free, low endotoxin (active trimer) (MALS verified) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Immobilized ActiveMax® Human TNF-alpha, Tag Free, low endotoxin (active trimer) (MALS verified) (Cat. No. TNA-H4211) at 2 ?g/mL (100 ?L/well) can bind Human TNFR1, Fc Tag (Cat. No. TN1-H5251) with a linear range of 0.2-3 ng/mL (Routinely tested).

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ActiveMax® Human TNF-alpha Protein, Tag Free, low endotoxin (active trimer) (MALS verified)

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