Human TNF-alpha Protein, premium grade
Product Code
AMS.TNA-H4211-100ug
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Tumor necrosis factor alpha (TNFC) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFC is in the regulation of immune cells. TNFC is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFC production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFC is used as an immunostimulant under the INN tasonermin. TNFC can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
SKU | AMS.TNA-H4211-100ug |
---|---|
Size | 100 ug |
Species | Human |
Expression Host | HEK293 |
Gene symbol | TNF-alpha |
aa sequence | Val 77 - Leu 233 |
Tag | Untagged |
Label/Conjugate | Unconjugated |
Accession No | NP_000585.2 |
Gene synonyms | DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFC |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |
Research Areas | Immunology |