Human TNF-alpha Protein, premium grade

Product Code
AMS.TNA-H4211-100ug
$240.00
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Tumor necrosis factor alpha (TNFC) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFC is in the regulation of immune cells. TNFC is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFC production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFC is used as an immunostimulant under the INN tasonermin. TNFC can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
More Information
SKU AMS.TNA-H4211-100ug
Size 100 ug
Species Human
Expression Host HEK293
Gene symbol TNF-alpha
aa sequence Val 77 - Leu 233
Tag Untagged
Label/Conjugate Unconjugated
Accession No NP_000585.2
Gene synonyms DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFC
Format Powder
Storage -20C
Shipping Temp RT
Supplier Name ACROBiosystems Inc.
Research Areas Immunology
For more details visit our ActiveMax® Human Cytokines page >