A 83-01

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A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs).
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SKU 1725-1
Size 1 mg
Application A TGF-beta type I receptor ALK5 kinase inhibitor
Cas no 909910-43-6
Storage -20C
Shipping Temp Gel Pack
Supplier Name BioVision
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