3CL Protease (B.1.1.529, Omicron Variant) (SARS-CoV-2) Assay Kit

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AMS.78350-2
$0.00
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The 3CL Protease (B.1.1.529, Omicron Variant) (SARS-CoV-2) Assay Kit is designed to measure the activity of P132H mutated, Omicron variant 3CL Protease for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.,The 3CL Protease Substrate is an internally quenched 14-mer fluorogenic (FRET) peptide (DABCYL-KTSAVLQSGFRKME-EDANS). When the donor (EDANS) and acceptor (DABCYL) fluorophores are in close proximity, the energy emitted from EDANS is quenched by DABCYL (intact substrate). Upon proteolysis by 3CL, the peptide substrate is cleaved between glutamine and serine to generate the highly fluorescent peptide fragment (SGFRKME-EDANS). The fluorescence intensity increases proportionally to the activity of 3CL. More information on the substrate, including MW and structure, can be found on our website ( AMSBIO , #79952).
More Information
SKU AMS.78350-2
Size 384 rxns.
Application Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.
Species reactivity SARS-CoV-2
Gene synonyms main protease kit, Mpro, SARS-CoV-2 3CL Protease kit, nsp5, 78350-1, 78350-2
Storage This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
Shipping Temp -80°C (dry ice)
Supplier Name BPS Bioscience Inc
For more details visit our SARS-CoV-2 Spike Mutants page >