3CL Protease (B.1.1.529|Omicron Variant) (SARS-CoV-2) Assay Kit

Name: 3CL Protease (B.1.1.529|Omicron Variant) (SARS-CoV-2) Assay Kit
Brand: AMS.78350-2
SKU: AMS.78350-2
Availability: InStock

Product Code

AMS.78350-2

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Overview

The 3CL Protease (B.1.1.529|Omicron Variant) (SARS-CoV-2) Assay Kit is designed to measure the activity of P132H mutated|Omicron variant 3CL Protease for screening and profiling applications|in a homogeneous assay with no time-consuming washing steps.The 3CL Protease Substrate is an internally quenched 14-mer fluorogenic (FRET) peptide (DABCYL-KTSAVLQSGFRKME-EDANS). When the donor (EDANS) and acceptor (DABCYL) fluorophores are in close proximity|the energy emitted from EDANS is quenched by DABCYL (intact substrate). Upon proteolysis by 3CL|the peptide substrate is cleaved between glutamine and serine to generate the highly fluorescent peptide fragment (SGFRKME-EDANS). The fluorescence intensity increases proportionally to the activity of 3CL. More information on the substrate|including MW and structure|can be found on our website ( Bioscience|#79952).

Product Specifications

More Information
SKU	AMS.78350-2
Size	384 reactions
Application	Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.
Species reactivity	SARS-CoV-2
Gene synonyms	main protease kit, Mpro, SARS-CoV-2 3CL Protease kit, nsp5, 78350-1, 78350-2
Storage	This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS

For more details visit our SARS-CoV-2 Spike Mutants page >

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ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

ALiCE® is a radically different approach to cell-free expression and a kit unlike any others.

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Prepared from Arthrobacter luteus, Zymolyase has a highly effective lytic activity against yeast cell walls.

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3CL Protease (B.1.1.529|Omicron Variant) (SARS-CoV-2) Assay Kit

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