Trevigen is the sole provider of a standardized CometAssay® system for the direct detection of DNA Damage.
The CometAssay® is a single cell gel electrophoresis assay which can be used to quantitate DNA Damage from in vivo or in vitro samples.
The CometAssay® measures double strand breaks (DSBs), single strand breaks (SSBs), alkali labile sites, oxidative DNA base damage, DNA-DNA/DNA-protein/DNA-Drug crosslinking and DNA repair.
At your request, the scientists at TCA will collaborate with you to design screening studies employing the CometAssay® tailored for your specific needs.
Advantages:
We use a unique platform of standardized comet assay kits, slides, control cells, CometAssayTM ES electrophoresis system (patent applied for) and state of the art image analysis to assure consistency of results with successive experiments or screening studies.
The technical team at Trevigen developed the reagents, slides, control cells and electrophoresis system, and are unmatched in their familiarity and skill with the comet assay.
We have already successfully executed multiple comet assay contracts and thus have a proven track record of high performance.
Confidentiality is assured. We are able to execute Non-Disclosure Agreements as required.
Coming Soon:
We will soon be expanding our services to offer study design and compound screening services for:
PARP.
PARG.
Cell invasion.
Cell migration.
Tube formation.
Pharmacodynamic PAR assays will also be offered.