Human Osteoprotegerin / TNFRSF11B Protein, Fc Tag

Name: Human Osteoprotegerin / TNFRSF11B Protein, Fc Tag
Brand: AMS.TNB-H5259-100ug
SKU: AMS.TNB-H5259-100ug
Price: 225 USD
Availability: InStock

Product Code

AMS.TNB-H5259-100ug

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$225.00

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Overview

Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) is also known as Osteoclastogenesis inhibitory factor (OCIF), Osteoprotegerin (OPG). TNFRSF11B is a secreted homodimer protein, which can interact with TNFSF10 and TNFSF11. TNFRSF11B acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TNFRSF11B inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Product Specifications

More Information
SKU	AMS.TNB-H5259-100ug
Size	100 ug
Species	Human
Expression Host	HEK293
Gene symbol	Osteoprotegerin
aa sequence	Glu 22 - Leu 401
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_002537
Gene synonyms	TNFRSF11B,OCIF,OPG,Osteoprotegerin
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Immobilized Human Osteoprotegerin, Fc Tag (Cat. No. TNB-H5259) at 5 ?g/mL (100 ?L/well) can bind Human TRAIL, Mouse IgG2a Fc Tag (Cat. No. TRL-H5259) with a linear range of 4-16 ng/mL (QC tested).

Human Osteoprotegerin, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.

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Human Osteoprotegerin / TNFRSF11B Protein, Fc Tag

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