Human TGF-beta RII / TGFBR2 Protein, Fc Tag (MALS verified)

Name: Human TGF-beta RII / TGFBR2 Protein, Fc Tag (MALS verified)
Brand: AMS.TG2-H5252-1mg
SKU: AMS.TG2-H5252-1mg
Price: 2725 USD
Availability: InStock

Product Code

AMS.TG2-H5252-1mg

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$2,725.00

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Overview

TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFCR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-C1 / TGFB1 and TGF-C3 / TGFB3 with high affinity and TGF-C2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

Product Specifications

More Information
SKU	AMS.TG2-H5252-1mg
Size	1 mg
Species	Human
Expression Host	HEK293
Gene symbol	TGF-beta RII
aa sequence	Thr 23 - Asp 159
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_003233
Gene synonyms	TGFBR2,TGFR2,TbetaR-II,TGFCR2
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Immobilized Human TGFB1, His Tag (Cat. No. TG1-H524x) at 1 ?g/mL (100 ?L/well) can bind Human TGFBR2, Fc Tag (Cat. No. TG2-H5252) with a linear range of 0.3-2 ng/mL (QC tested).

Human TGFBR2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Human TGF-beta RII / TGFBR2 Protein, Fc Tag (MALS verified)

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