Mouse PD-L2 / B7-DC Protein, Fc Tag

Name: Mouse PD-L2 / B7-DC Protein, Fc Tag
Brand: AMS.PD2-M5254-100ug
SKU: AMS.PD2-M5254-100ug
Price: 365 USD
Availability: InStock

Product Code

AMS.PD2-M5254-100ug

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$365.00

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Overview

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Product Specifications

More Information
SKU	AMS.PD2-M5254-100ug
Size	100 ug
Species	Mouse
Expression Host	HEK293
Gene symbol	PD-L2
aa sequence	Leu 20 - Arg 219
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_067371
Gene description	Mouse
Gene synonyms	PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Immobilized Mouse PD-L2, Fc Tag (Cat. No. PD2-M5254) at 5 ?g/mL (100 ?L/well) can bind Mouse PD-1, mouse IgG2a Fc tag (Cat. No. PD1-M52A4) with a linear range of 0.078-0.625 ?g/mL (QC tested).

Mouse PD-L2, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Mouse PD-L2 / B7-DC Protein, Fc Tag

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