Human OX40 Ligand / TNFSF4 Protein, Mouse IgG2a Fc Tag, low endotoxin

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AMS.OXL-H5250-1mg
$3,175.00
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Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.
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SKU AMS.OXL-H5250-1mg
Size 1 mg
Species Human
Expression Host HEK293
Gene symbol OX40 Ligand
aa sequence Gln 51 - Leu 183
Tag FC
Label/Conjugate Unconjugated
Accession No NP 003317.1
Gene synonyms OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L
Format Powder
Storage -20C
Shipping Temp RT
Supplier Name ACROBiosystems Inc.