Human NKp30 / NCR3 / CD337 Protein, Fc Tag

Product Code
AMS.NC3-H5259-100ug
$350.00
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Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
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SKU AMS.NC3-H5259-100ug
Size 100 ug
Species Human
Expression Host HEK293
Gene symbol NKp30
aa sequence Leu 19 - Gly 135
Tag FC
Label/Conjugate Unconjugated
Accession No AAH52582
Gene synonyms NCR3,CD337,NKp30,1C7,LY117,MALS
Format Powder
Storage -20C
Shipping Temp RT
Supplier Name ACROBiosystems Inc.