Human IL-2 R alpha / CD25 Protein, Fc Tag (MALS verified)

Name: Human IL-2 R alpha / CD25 Protein, Fc Tag (MALS verified)
Brand: AMS.ILA-H5251-1mg
SKU: AMS.ILA-H5251-1mg
Price: 2200 USD
Availability: InStock

Product Code

AMS.ILA-H5251-1mg

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$2,200.00

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Overview

Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.

Product Specifications

More Information
SKU	AMS.ILA-H5251-1mg
Size	1 mg
Species	Human
Expression Host	HEK293
Gene symbol	IL-2 R alpha
aa sequence	Glu 22 - Cys 213
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_000408
Gene description	Human
Gene synonyms	IL2RA,CD25,p55,IL2-RA,IL-2-RA
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Immobilized Human IL-2 R alpha, Fc Tag (Cat. No. ILA-H5251) at 2?g/mL (100 ?L/well) can bind Human IL-2, Tag Free (Cat. No. IL2-H4113) with a linear range of 0.2-1.56 ng/mL (QC tested).

Human IL-2 R alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Human IL-2 R alpha / CD25 Protein, Fc Tag (MALS verified)

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