Human Gremlin / GREM1 Protein, Fc Tag

Name: Human Gremlin / GREM1 Protein, Fc Tag
Brand: AMS.GR1-H5254-100ug
SKU: AMS.GR1-H5254-100ug
Price: 390 USD
Availability: InStock

Product Code

AMS.GR1-H5254-100ug

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$390.00

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Overview

Gremlin is also known as Cysteine knot superfamily 1, BMP antagonist 1 (CKTSF1B1), DAN domain family member 2 (DAND2), Down-regulated in Mos-transformed cells protein (DRM), Increased in high glucose protein 2 (IHG-2), Cell proliferation-inducing gene 2 protein (PIG2) or Gremlin-1 (GREM1), which is highly expressed in small intestine, fetal brain and colon. Gremlin / GREM-1 interacts with SLIT1 and SLIT2 in a glycosylation-dependent manner. Gremlin may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Gremlin down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis.

Product Specifications

More Information
SKU	AMS.GR1-H5254-100ug
Size	100 ug
Species	Human
Expression Host	HEK293
Gene symbol	Gremlin
aa sequence	Lys 25 - Asp 184
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_037504
Gene synonyms	GREM1,CKTSF1B1,DAND2,DRM,PIG2
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.
Research Areas	Immunology

Images

Immobilized Human BMP-2, Tag Free (Cat. No. BM2-H4117) at 2?g/mL (100 ?L/well) can bind Human Gremlin, Fc Tag (Cat. No. GR1-H5254) with a linear range of 0.8-80 ng/mL (QC tested).

Human Gremlin, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Human Gremlin / GREM1 Protein, Fc Tag

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