Human GITR Ligand / TNFSF18 Protein, Fc Tag
Product Code
AMS.GIL-H526a-1mg
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Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
SKU | AMS.GIL-H526a-1mg |
---|---|
Size | 1 mg |
Species | Human |
Expression Host | HEK293 |
Gene symbol | GITR Ligand |
aa sequence | Gln 50 - Ser 177 |
Tag | FC |
Label/Conjugate | Unconjugated |
Accession No | AAH69319.1 |
Gene synonyms | TNFSF18,AITRL,TL6,hGITRL,GITR Ligand |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |