Human Frizzled-5 / FZD5 Protein, Fc Tag
Product Code
AMS.FZ5-H5259-100ug
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Frizzled-5 (FZD5) is also known as FzE5, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta-catenin pathway. FZD5 interacts with GOPC.
SKU | AMS.FZ5-H5259-100ug |
---|---|
Size | 100 ug |
Species | Human |
Expression Host | HEK293 |
Gene symbol | Frizzled-5 |
aa sequence | Ala 27 - Pro 167 |
Tag | FC |
Label/Conjugate | Unconjugated |
Accession No | Q13467 |
Gene synonyms | FZD5,Frizzled-5,C2orf31,,Fz-5,hFz5,FzE5 |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |