Human Frizzled-4 / FZD4 Protein, Fc Tag
Product Code
AMS.FZ4-H5250-1mg
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Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).
| SKU | AMS.FZ4-H5250-1mg |
|---|---|
| Size | 1 mg |
| Species | Human |
| Expression Host | HEK293 |
| Gene symbol | Frizzled-4 |
| aa sequence | Phe 37 - Glu 180 |
| Tag | FC |
| Label/Conjugate | Unconjugated |
| Accession No | AAI14528 |
| Gene synonyms | FZD4,Frizzled-4,CD344,Fz-4,hFz4,FzE4 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | RT |
| Supplier Name | ACROBiosystems Inc. |
