Human E-Cadherin / Cadherin-1 Protein, Fc Tag, premium grade

Name: Human E-Cadherin / Cadherin-1 Protein, Fc Tag, premium grade
Brand: AMS.ECD-H5250-100ug
SKU: AMS.ECD-H5250-100ug
Price: 325 USD
Availability: InStock

Product Code

AMS.ECD-H5250-100ug

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$325.00

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Overview

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-1 (CDH1) is also known as epithelial cadherin (E-cadherin), CD_antigen (CD324), Uvomorulin (UVO) ECAD and CDHE, CDH1 / CD324 contains 5 cadherin domains. CDH1 / CD324 / ECAD is expressed in non-neural epithelial tissues. CDH1 / E-CAD is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad promotes non-amyloidogenic degradation of Abeta precursors and has a strong inhibitory effect on APP C99 and C83 production. Defects in CDH1 / CD324 / ECAD are the cause of hereditary diffuse gastric cancer (HDGC).

Product Specifications

More Information
SKU	AMS.ECD-H5250-100ug
Size	100 ug
Species	Human
Expression Host	HEK293
Gene symbol	E-Cadherin
aa sequence	Gln 23 - Pro 621
Tag	FC
Label/Conjugate	Unconjugated
Accession No	AAI41839
Gene description	Human
Gene synonyms	Cadherin-1,CDH1,CD324,E-cadherin,Arc-1,ECAD,LCAM,UVO
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Human E-Cadherin, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Human E-Cadherin / Cadherin-1 Protein, Fc Tag, premium grade

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