Human DNAM-1 / CD226 Protein, Fc Tag

Name: Human DNAM-1 / CD226 Protein, Fc Tag
Brand: AMS.DN1-H5257-100ug
SKU: AMS.DN1-H5257-100ug
Price: 315 USD
Availability: InStock

Product Code

AMS.DN1-H5257-100ug

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$315.00

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Overview

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

Product Specifications

More Information
SKU	AMS.DN1-H5257-100ug
Size	100 ug
Species	Human
Expression Host	HEK293
Gene symbol	DNAM-1
aa sequence	Glu 19 - Asn 247
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_006557
Gene synonyms	DNAM1,CD226,PTA1
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Immobilized Rhesus macaque CD155 (Cat. No. CD5-R52H5) at 5 ?g/mL (100 ?L/well) can bind Human DNAM-1, Fc Tag (Cat. No. DN1-H5257) with a linear range of 2-31 ng/mL (QC tested).

Human DNAM-1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Human DNAM-1 / CD226 Protein, Fc Tag

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