Mouse LILRB4 / CD85k / ILT3 Protein, Fc Tag
Product Code
AMS.CDK-M5250-100ug
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Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
| SKU | AMS.CDK-M5250-100ug |
|---|---|
| Size | 100 ug |
| Species | Mouse |
| Expression Host | HEK293 |
| Gene symbol | LILRB4 |
| aa sequence | Gly 24 - Lys 238 |
| Tag | FC |
| Label/Conjugate | Unconjugated |
| Accession No | NP_038560.1 |
| Gene description | Mouse |
| Gene synonyms | LILRB4,ILT3,LIR5,CD85K,HM18 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | RT |
| Supplier Name | ACROBiosystems Inc. |
