Human LILRB1 / CD85j / ILT2 Protein, Fc Tag (MALS verified)
Product Code
AMS.CDJ-H5252-1mg
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CD85 antigen-like family member J (CD85J) is also known as Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1 or LIR-1), Immunoglobulin-like transcript 2 (ILT-2), Monocyte/macrophage immunoglobulin-like receptor 7 (MIR7), which belongs to leukocyte immunoglobulin-like receptor (LIR) family. CD85J / LILRB1 Contains 4 Ig-like C2-type (immunoglobulin-like) domains. CD85J / LIR-1 is expressed predominantly on B-cells and monocytes. CD85J is receptor for class I MHC antigens and recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles and is also receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. CD85J / LILRB1 interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. CD85J / LILRB1 inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
| SKU | AMS.CDJ-H5252-1mg |
|---|---|
| Size | 1 mg |
| Species | Human |
| Expression Host | HEK293 |
| Gene symbol | LILRB1 |
| aa sequence | Gly 24 - His 458 |
| Tag | FC |
| Label/Conjugate | Unconjugated |
| Accession No | AAH15731.1 |
| Gene id | Human LILRB1, Fc Tag (CDJ-H5252) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - His 458 (Accession # D9IDM8-1). |
| Gene synonyms | CD85J,LILRB1,CD85,ILT2,LIR1,MIR7 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | RT |
| Supplier Name | ACROBiosystems Inc. |
