Mouse BAFFR / TNFRSF13C Protein, Fc Tag (HPLC verified)

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AMS.BAR-M5259-100ug
$395.00
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BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
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SKU AMS.BAR-M5259-100ug
Size 100 ug
Species Mouse
Expression Host HEK293
Gene symbol BAFFR
aa sequence Ser 10 - Ala 71
Tag FC
Label/Conjugate Unconjugated
Accession No NP_082351.1
Gene description Mouse
Gene synonyms BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R
Format Powder
Storage -20C
Shipping Temp RT
Supplier Name ACROBiosystems Inc.