PD-1[Biotinylated]:PD-L1 Inhibitor Screening Colorimetric Assay Kit
Product Code
72018
$0.00
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Cell signaling through the PD-1 receptor upon binding the PD-L1 ligandattenuates immune responses and is exploited by both tumors and viruses. The PD-1[Biotinylated]:PD-L1 Inhibitor Colorimetric Screening Assay Kit is designed for screeninginhibitors of PD-1 receptor binding to PD-L1 ligand. This kit comes in a convenient 96-wellformat|with biotin-labeled PD-1|purified PD-L1|streptavidin-labeled HRP|and assay buffer for100 binding reactions. The key to this kit is the high affinity of biotin-labeled PD-1 forstreptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First|PD-L1 is coated on a 96-well plate. Next|PD-1 is incubated with PD-L1 on the plate. Finally|theplate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate toproduce color|which can then be measured using a UV/Vis spectrophotometer microplatereader.
SKU | 72018 |
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Size | 96 reactions |
Alternate SKU | AMS.72018 |
Application | This kit is most useful for screening for inhibitors of PD-L1. |
Gene synonyms | Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L and Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7-H1) |
Storage | Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |
Research Areas | Immunology |