CD40/NF-kappaB Luciferase Reporter HEK293 Cell Line

Name: CD40/NF-kappaB Luciferase Reporter HEK293 Cell Line
Brand: 60626
SKU: 60626
Availability: InStock

Product Code

60626

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Overview

Recombinant HEK293 cell line expressing full length human CD40 (Tumor necrosis factor receptor superfamily member 5; TNFRSF5). Expression is confirmed by flow cytometry and Western Blot. This NF-kappaB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by human CD40 ligand/ NF-kappaB transcription factor binds to the DNA response elements to induce transcription of the luciferase gene.

Product Specifications

More Information
SKU	60626
Size	2 vials
Alternate SKU	AMS.60626
Species	Human
Cell Line	HEK293
Tissue Type	Kidney
Application	The CD40 NF-kappaB Reporter HEK293 Stable Cell Line is ideal for High Throughput Screening (HTS) to identify potential CD40 agonistic monoclonal antibodies and CD40-specific inhibitors.
Gene synonyms	CD40 cell line, luciferase reporter, CD40 NF-kB cell line, NFkB cell line
Storage	Immediately upon receipt/ store vials in liquid nitrogen.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS
Research Areas	Immunology

For more details visit our Immunotherapy page >

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Citations

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CD40/NF-kappaB Luciferase Reporter HEK293 Cell Line

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