TIGIT / NFAT Reporter - Jurkat Cell Line

Product Code
60538
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Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (Tcell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3)/ and a firefly luciferasegene under the control of nuclear factor of activator T cells (NFAT) response element. BothTIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression hasbeen confirmed by Western Blot/ and TIGIT-specific NFAT response has been validated using aTIGIT ligand/ CD155 (PVR).
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SKU 60538
Size 2 vials
Alternate SKU AMS.60538
Species Human
Cell Line JURKAT
Tissue Type Lymphoid Tissue
Application This cell line is ideal for high throughput screening (HTS) to identify antagonistic monoclonal antibodies targeting either TIGIT or its ligands/ such as CD155 in a cellular context.
Gene synonyms T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, VSIG9, V-set and transmembrane domain-containing protein 3, VSTM3
Storage Store in liquid nitrogen immediately upon receipt.
Shipping Temp -80C (dry ice)
Supplier Name BPS
Research Areas Immunology
For more details visit our Immunotherapy page >