amsbio supplies
Cultrex® &
CultreCoat® Cell Invasion Assays created to accelerate
the screening process for compounds that influence cell migration through extracellular matrices -
Download Brochure (2.07MB)
These assays offer a flexible, standardized, high throughput format for quantitating the degree to which invasive cells penetrate a barrier consisting of basement membrane components
in vitro
in response to chemoattractants and/or inhibiting compounds. The Cultrex
® Cell Invasion Assay has been adapted to multiple formats so that cell invasion may be evaluated against different extracellular matrices
including:
Basement Membrane Extract (BME),
Laminin I,
Collagen I,
Collagen IV.
CultreCoat® Cell Invasion Assay Features:
- Pre-coated inserts save time
- Pre-coated inserts improve reproducibility of results
- Complete kit format
- Coating process assures uniform matrix layer to minimize variability
Cultrex® Cell Invasion Assay Features:
- Includes matrix, coating solution, invasion chamber, buffers and Calcein AM
- Functionally tested with MCF, HT1080, NIH3T3 and MDA-MB231 cells
- QC to ensure invasive MDA-MB231 cells penetrate an 8 micron BME coated membrane and non-invasive MCF7 cells do not
- Available in 96 and 24 well formats