Extracellular Matrices, Matrigel
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Cell and Cell Culture
Cells do not exist as single cell entities in nature; they are always part of a larger multicellular organism supported by extracellular matrix (ECM). In tissue culture, the ECM represents a critical biologically active interface in direct contact with the cell that should provide optimal environmental conditions to promote physiologically relevant cellular structure and function. In addition to maintaining growth factor signalling, ECM provides essential integrin binding events that inhibit anoikis (anchorage-dependent cell death).
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AMS Biotechnology (Europe) Limited,
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