Adeno-associated viruses are single-stranded DNA viruses that can infect a broad range of cell types including dividing and non-dividing cells and are,
therefore, widely used vehicles for gene delivery.
Clinical trials have not only found AAV to be consistently safe, but their vectors are capable of causing long-term
expression in human cells.
Therefore, AAV vectors have many advantages that many other vectors do not.
To date, recombinant AAV (rAAV) vectors have been used in many clinical trials in gene therapy, and have achieved promising results
from Phase 1 and Phase 2 trials. Trials have been run on diseases such as Cystic Fibrosis, Haemophilia B, Arthritis
and Parkinson's disease.
- Transfect both dividing and non-dividing cells
- No host-genome integration & stable expression
- Ease to produce at high viral titre (helper free)
- Does not elicit significant immune response in vivo
- Can be used for in vivo gene deliveries
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Read the current status of AAV vectors being used in cancer gene therapy
Read about the latest development in AAV technology
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AMSBIO offers the highest quality rAAV vectors and the most complete AAV Expression Systems
that can be used to express shRNA, or human ORF. Through proprietary technology and innovative AAV vectors, you'll
get reliable, reproducible, high purity, high titre viral stock every time you order.
Working with AMSBIO saves your time and increases efficiency at the most cost-effective price
AMSBIO has the most robust and professional AAV packaging service, ranging from the small crude scale
to the large purified scale.
We have the platform that suits all your needs when it comes to combining scientific discovery and processing
advancements in the field of gene therapy. With AMSBIO's AAV production system, using AAV as a
therapeutic vehicle for a broad range of diseases is now a simple task.